Indication
Atipamezol hydrochloride is used in dogs and cats to reverse the sedative and cardiovascular effects of α2-agonists such as medetomidine and dexmedetomidine.
Atipamezol hydrochloride is used in dogs and cats to reverse the sedative and cardiovascular effects of α2-agonists such as medetomidine and dexmedetomidine.
– Dogs: Atipamezol is injected intramuscularly. The optimal dose in micrograms per kilogram is five times the previous medetomidine dose or ten times the previous dexmedetomidine dose. The reversal dose in milliliters is the same as the dose of medetomidine 1 mg/ml or dexmedetomidine 0.5 mg/ml. The reversal dose for dexmedetomidine 0.1 mg/ml is one-fifth of the volume. The product can also be used post-surgery to reverse the effects of medetomidine or dexmedetomidine and accelerate recovery, especially when combined with butorphanol or used during pre-anesthesia with thiopental-halothane or propofol in dogs.
– Cats: Atipamezol is injected intramuscularly. The optimal dose in micrograms per kilogram is 2.5 times the previous medetomidine dose or 5 times the previous dexmedetomidine dose. The reversal dose in milliliters is half of the dose for medetomidine 1 mg/ml or dexmedetomidine 0.5 mg/ml, and one-tenth of the dose for dexmedetomidine 0.1 mg/ml.
Dog:
| Medetomidin dose | Deksmedetomidin 0.5 mg/ml dose | Deksmedetomidin 0.1 mg/ml dose | Reversal dose |
|---|---|---|---|
| 40 mcg/kg | 20 mcg/kg | 20 mcg/kg | 200 mcg/kg |
| = 0.4 ml/10 kg | = 0.4 ml/10 kg | = 2.0 ml/10 kg | = 0.4 ml/10 kg |
Cat:
| Medetomidin dose | Deksmedetomidin 0.5 mg/ml dose | Deksmedetomidin 0.1 mg/ml dose | Reversal doz |
|---|---|---|---|
| 80 mcg/kg | 40 mcg/kg | 40 mcg/kg | 200 mcg/kg |
| = 0.4 ml/5 kg | = 0.4 ml/5 kg | = 2.0 ml/3 kg* | = 0.2 ml/5 kg, 0.12 ml/3 kg |
For cats weighing over 3 kg, **dexmedetomidine 0.5 mg/ml** is recommended. The dose in micrograms per kilogram should not exceed four times the previously administered medetomidine dose or eight times the previously administered dexmedetomidine dose.
In cases where medetomidine or dexmedetomidine is used for anesthesia in cats, either with or without butorphanol and ketamine, this product can be used to reverse the effects of medetomidine or dexmedetomidine and accelerate recovery post-anesthesia.
In this scenario, the dosage of the veterinary product for recovery will be the same as the one used after a single administration of medetomidine or dexmedetomidine, but the product should not be administered earlier than 30 to 40 minutes after ketamine administration.
This product is not intended for use in food-producing animals.
Available in 10 ml amber-colored type II glass vials with a transparent flip-off cap and gray bromobutyl stopper, packaged in a carton box.
Bir Alivira Grup Şirketi
Çavuşoğlu Mah. Başkumandan Caddesi No:28 Kartal / İstanbul
Çekirdeksiz Organize Sanayi Bölgesi 210. Cad. No: 7 06900 Polatlı / Ankara
