Tomidin

Dogs;
As a sedative, 750 µg is applied intravenously per square meter of body surface area or 1,000 µg is applied intramuscularly. The intravenous dose is 80 µg / kg body weight (0.08 ml / kg), and the intramuscular dose is 100 µg / kg body weight (0.1 ml / kg). Since the dose does not increase proportionally with body weight, the following dose table should be followed in practical application

Pre-anesthetic Use in Dogs:

Tomidin – Levometadon
For sedation, 20 – 40 µg of medetomidine and 0.25 – 0.50 mg/kg of Levometadon are administered together as an intravenous injection.

Tomidin – Ketamine
For abdominal and mild orthopedic surgeries, sedation can be achieved by using 30 – 40 µg of medetomidine with 2 – 5 mg/kg of ketamine. Tomidin and ketamine can be administered via separate syringes intramuscularly or ketamine can be given 10 – 15 minutes after Tomidin injection.

Tomidin – Propofol
Medetomidine can be administered intravenously 10 minutes before propofol injection or intramuscularly 20 minutes before. In practical application, the following table can be used

Tomidin – Thiopental
Medetomidine is administered intravenously 10 minutes before thiopental injection or intramuscularly 20 minutes before. In practical application, the following table can be used

Injection should be administered intravenously within a 30-40 second period. After achieving relaxation in the mouth area, tracheal intubation can be performed using Halothane or Isoflurane. The recovery period after inhalation anesthesia may take 20-60 minutes. Atipamezole administration shortens this recovery time.

Tomidin – Halothane
Medetomidine can be applied intravenously or intramuscularly as premedication at a dose of 10-40 µg/kg in halothane/oxygen or halothane/nitrous oxide/oxygen anesthesia, or combined with thiopental, propofol, or halothane. The amount of anesthetic injected or inhaled with Tomidin can be reduced, so halothane should be applied in a controlled manner until the desired anesthetic effect is achieved.

Tomidin – Isoflurane
Medetomidine can be used for premedication at a dose of 10-40 µg/kg body weight in isoflurane/oxygen or isoflurane/nitrous oxide/oxygen anesthesia. About 20 minutes after administration, when Tomidin has reached its maximum sedative effect, general anesthesia can be induced with thiopental, propofol, or Isoflurane. The amount of isoflurane required is reduced with the use of Tomidin. If respiratory depression occurs, oxygen should be administered with a mask

Use in Cats:
For sedation in cats, medetomidine is administered at a dose of 80 µg/kg body weight (0.08 ml/kg) along with 5 – 7.5 mg/kg body weight of ketamine. Tomidin and ketamine can be administered intramuscularly in the same syringe. With this dose, the anesthetic effect begins 3 – 4 minutes after administration and lasts for 20 – 50 minutes. In prolonged operations, the dose may be increased later. For this purpose, 50% of the initial dose (40 µg/kg body weight of medetomidine + 2.5 – 3.75 mg/kg body weight of ketamine) or 3 mg/kg body weight of ketamine alone should be administered. Alternatively, a halothane/oxygen mixture or, in addition, nitrous oxide inhalation can be applied.

Animals should be fasted for 12 hours before anesthesia. In long-term applications, dryness of the eyes should be treated with suitable preparations.
After administration, food and water should not be given until the swallowing reflex returns